The Jackson Lab
Studying The Molecular and Cell Biology of Picornaviruses
Our focus is to understand how viruses do such an excellent job of invading our cells and turning them into virus production factories.
Our lab studies poliovirus, coxsackievirus, enterovirus D68, enterovirus 71, and rhinovirus, the common cold virus.
About our work
The Jackson Lab is primarily interested in understanding the biology of these simplest human viruses, all members of the family picornaviridae. While they are simple and tiny - even for viruses - they cause an astounding amount and variety of human disease. Picornaviruses (the "pico" is for tiny and the "rna" refers to the genetic material) can cause hepatitis, foot-and-mouth disease, poliomyelitis, and the common cold, to name a few diseases.
SIRT-1 is required for release of enveloped picornaviruses
Starvation after infection restricts enterovirus D68 replication
SNAP23 is essential for germination of EV-D68 replication organelles
Email Dr. Jackson at
Mail: HSF-I Room 385
685 W Baltimore St
Baltimore, MD 21201
Lab Phone: 410-706-4906